Birc6 protein folding

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August undefined, 2024

WebThe BIRC6 protein is at 528 kDa, an unusually large member of the IAP family. It consists of a single N-terminal BIR domain and a C-terminal ubiquitin-conjugating (UBC) domain; the latter Webralph lauren mens shoes sale; harmony collection clothing; MON-SAT 10:00AM - 7:00PM PST

Tissue Cell Type - BIRC6 - The Human Protein Atlas

WebDec 2, 2024 · Inhibitors of apoptosis proteins (IAPs) have been associated with tumor development and progression by affecting apoptosis through cell death signaling pathways. To date, eight IAPs (BIRC1–8) have been identified in mammalian cells. However, the role of IAPs in non–small cell lung cancer (NSCLC) development and progression has not … WebOriginal Article Overexpression of BIRC6 driven by EGF-JNK-HECTD1 signaling is a potential therapeutic target for triple-negative breast cancer Yongpeng Li,1 ,2 10Yanan Tan,34 Lijuan Wen,5 Zhihao Xing,6 Changxu Wang,7 Liuhui Zhang,8 Kai Wu,1 Haiyan Sun, 1Yuqing Li, Qifang Lei,1 and Song Wu ,9 1The Third Afﬁliated Hospital of Shenzhen … simonis clifford chance

AI for protein folding - MIT Technology Review

WebBIRC6 (BRUCE) protein expression summary. Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein li gase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 … WebBIRC6. TISSUE CELL TYPE TISSUES. ADIPOSE SUBCUTANEOUS ADIPOSE VISCERAL BREAST COLON HEART MUSCLE KIDNEY LIVER LUNG. PANCREAS PROSTATE SKELETAL MUSCLE SKIN STOMACH TESTIS THYROID. Cell type enrichment. ... The Human Protein Atlas project is funded by the Knut & Alice Wallenberg Foundation. ... simonis factory flood

National Center for Biotechnology Information

Brain tissue expression of BIRC6 - Summary - Protein Atlas

WebThis gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. Interactions. BIRC6 has been shown to interact with KIF23. Diseases WebBIRC6 is part of cluster 45 Non-specific - Cell proliferation with confidence i ... RAN binding protein 2: 0.4987: 45: SNRNP200: Small nuclear ribonucleoprotein U5 subunit 200: 0.4809: 45: PSME4: Proteasome activator subunit 4: 0.4785: 45: VPS13C: Vacuolar protein sorting 13 homolog C: 0.4776: 45: ZNF638: simonis-beattyWebJul 12, 2012 · BIRC6 is an inhibitor of apoptosis protein (IAP), that can bind and degrade the cytoplasmic fraction of the pro-apoptotic protein DIABLO. DIABLO mRNA expression was exceptionally high in neuroblastoma but the protein was only detected in the mitochondria. Upon silencing of BIRC6 by shRNA, DIABLO protein levels increased and … simonis camel blue on pool table pics

"WebMar 14, 2024 · BIRC6 is a large protein (528 kDa) with pleiotropic functions, including inhibition of apoptosis, cytoprotection and regulation of cytokinesis , and mitosis . Its activity is upregulated in many cancers, including prostate cancer, particularly CRPC ( 9 ), associated with poor patient prognosis ( 10–14 ), and shown to enhance … " - Birc6 protein folding

Birc6 protein folding

BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival

WebNational Center for Biotechnology Information WebBIRC6. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. …

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WebThis gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein … This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination.

WebMar 21, 2024 · BIRC6 (Baculoviral IAP Repeat Containing 6) is a Protein Coding gene. Diseases associated with BIRC6 include Brain Cancer and Schizophrenia . Among its related pathways are Signaling by ALK in cancer and Disease . Gene Ontology (GO) … TP53 (Tumor Protein P53) is a Protein Coding gene. Diseases associated with … WebA lentivirus-mediated silencing method was used to knockdown BIRC6, and the biological con-sequences of BIRC6 silencing in three hepatoma cell lines were investigated in vitro and in vivo. We found that BIRC6 overexpres-sion was significantly correlated with serum ALT level and HCC vascular invasion. Patients with positive BIRC6 expression in tumor

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WebSep 27, 2024 · In addition, CHX chase assays showed that HECTD1 overexpression accelerated BIRC6 protein degradation (Figure 3D), whereas BIRC6 protein was more stable after HECTD1 knockdown (Figure 3E). To further investigate whether degradation of BIRC6 was mediated through ubiquitination, we cotransfected 293T cells with Myc …

WebFeb 8, 2013 · Background BIRC6 is a member of the Inhibitors of Apoptosis Protein (IAP) family which is thought to protect a variety of cancer cells from apoptosis. The main objective of the present study was to investigate … simoniseren beste productWebMar 21, 2024 · Complete information for BIRC6-AS1 gene (RNA Gene), BIRC6 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. … simonis 9 ft. 760 pool table clothWebFeb 10, 2024 · Abstract. Background: Baculoviral IAP repeat containing 6 (BIRC6), a member of the inhibitors of apoptosis protein (IAP) family, has been reported to be correlated with oncogenesis. The aim of this study was to investigate the prognostic significance of BIRC6 in prostate cancer, as well as its effects on prostate cancer cell lines. simonise cats to buyWebMar 21, 2024 · Complete information for BIRC6-AS1 gene (RNA Gene), BIRC6 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... BIRC6 Antisense RNA 1 (Non-Protein Coding) (HGNC, NCBI Entrez Gene) NONHSAG027421.2 ; HSALNG0146433 ; BIRC6 … simonis-corwinWebFeb 23, 2024 · A protein is made up of a ribbon of amino acids, which folds up into a knot of complex twists and twirls. Determining that shape—and thus the protein’s function—can take months in a lab. simonis fast 42WebBirc6 Human gene description i. Baculoviral IAP repeat containing 6: Predicted location i Intracellular: Mouse gene: ENSMUSG00000024073 (version 103) Pig gene: ENSSSCG00000008513 (version 103) Antibodies in assay i. No antibodies in assay HUMAN PROTEIN ATLAS INFORMATION; Tissue specificity i. Low tissue specificity ... simonis-cruickshankWebAşılar Sizi veya Kolunuzu Manyetik Yapmaz; Yapamaz! - Evrim Ağacı simonis copy horaire