TīmeklisHighly specific and rigorously validated in-house, EED Antibody (CST #51673) is ready to ship. ... The first complex, EED-EZH2, is recruited to genes by DNA-binding … TīmeklisThe tissue slices were incubated with the rabbit anti-EZH2 antibody (1:150 dilution, CST) or rabbit anti-Ki67 antibody (1:250 dilution, Abcam) overnight at 4°C. After washing with PBS the next day, the tissue slices were incubated with the secondary antibody for 30 min at room temperature and then with horseradish peroxidase for 20 min. DAB ...
Phospho-EZH2 (Thr367) Polyclonal Antibody - Thermo Fisher Scientific
TīmeklisFigure 3 . Knockdown of EZH2 reduces apoptosis and inflammatory responses in vitro. (A) Expression of EZH2, cleaved-caspase3, Bax, and Bcl2 in HK-2 cells with or without shEZH2 was detected by western blotting and quantified by densitometry.(B)The levels of TNF-α, IL-6 and IL-1β were determined by qPCR. (C) Cell activity was determined … Tīmeklis2024. gada 11. febr. · Increasing evidence has suggested that EZH2 is involved in altering the metabolic profiles of tumor cells by multiple pathways, which cover glucose, lipid and amino acids metabolism. EZH2 methyltransferase activity can facilitate adipogenesis. Severe defects of adipogenesis in Ezh2 −/− mouse primary … shipping centre
EZH2 Polyclonal Antibody (49-1043) - Thermo Fisher Scientific
Tīmeklis2024. gada 13. nov. · In terms of mechanism, we illustrate that meR342-EZH2 facilitates EZH2 binding with SUZ12 and PRC2 assembly by preventing AMPKα1-mediated phosphorylation of pT311-EZH2, which results in ... Tīmeklis2024. gada 7. febr. · Multiple myeloma (MM) is the second most common hematological malignancy with poor prognosis. Enhancer of zeste homolog 2 (EZH2) is the … Tīmeklis2024. gada 26. jūn. · EZH2 mediates H3K27me3 modification, which is associated with chromatin compaction and gene silencing. Thus, EZH2 knockdown decreases the overall level of H3K27me3, thereby activating gene expression. shipping centre al