WebAug 2, 2013 · Moreover, analogous to loss-of-function mutations in JPH2, we hypothesize that FGF13 mutations may lead to “orphaned ryanodine receptors” that are no longer apposed to Ca V 1.2, and thus may be associated with heart failure. 20 Further studies in the appropriate model are necessary to test that hypothesis. WebFGF13 Mutation Back to Biomarkers List Associated Genetic Biomarkers Associated Diseases Overview Gene Location [ 1] Xq26.3-q27.1 Gene FGF13 Clinical Trials View Clinical Trials for FGF13 Mutation Significance of FGF13 Mutation in Diseases Urothelial Carcinoma + Cancer + Cholangiocarcinoma + Endometrial Carcinoma + Gastric …
Fibroblast growth factor homologous factor 13 regulates Na
WebFgf13 deficiency resulted in decreased SGN density from the apical to the basal region without significant morphological changes and those in the number of hair cells. TUNEL and caspase-3... WebFGF13 was shown to directly bind to and colocalize with Na v 1.5 in mouse cardiac cells. Reducing the expression of FGF13 decreased the Na + current, shifted the availability curve toward more negative potentials, and slowed recovery from inactivation. olympus vn 7200 manual pdf
Elmo1 overexpression in hippocampal neurons affects axonal …
WebJan 22, 2024 · FGF13 provided by HGNC Official Full Name fibroblast growth factor 13 provided by HGNC Primary source HGNC:HGNC:3670 See related Ensembl ... Domain Mapping of Disease Mutations; FGF13; Eukaryotic Promoter Database; FGF13_1; GenScript latest version of gene cDNA ORF Clone; GenScript latest version of gene … WebJun 29, 2024 · The human FGF13 sequence was highly conserved among many species including the mouse (Figure 2A), then we constructed the homologous mouse 5′-UTR … WebThis deletion encompassed only one gene, Fibroblast Growth Factor Homologous Factor 13 (FGF13), which encodes a 216-amino acid protein that acts intracellularly in neurons … olympus vn 702pc user manual